V. Gonnot, Marc Nicolas, C. Mioskowski
Nov 1, 2009
Citations
0
Influential Citations
5
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
A short and straightforward synthesis of the antihistaminic drug mequitazine is reported, based on an efficient palladium catalyzed allylic alkylation of 1-aza-bicyclo[2.2.2]oct-2-en-3-ylmethyl acetate using sodium phenothiazinate in mild conditions.