J. R. Catch, A. R. Graham, A. H. Cook
Apr 26, 1947
Citations
0
Influential Citations
5
Citations
Journal
Nature
Abstract
OF several recent syntheses of dl-methionine, that commencing with γ-butyrolactone1 is relatively long, while others2 are additionally inconvenient in that they employ methyl-β-chloroethylsulphide, a vesicant intermediate. It seems, therefore, desirable to state that the following series of reactions has been found to afford an overall yield of dl-methionine of 29 per cent (that is, based on acrolein), and to be free from disadvantages such as those mentioned above: