S. N. Lavrenov, S. A. Lakatosh, L. Lysenkova
2002
Citations
0
Influential Citations
3
Citations
Journal
Synthesis
Abstract
Indoline-2-carboxylic acid was transformed into 6-nitroindoline-2-carboxylic acid, the methyl ester of which was easily dehydrogenated by DDQ to methyl 6-nitroindole--2-carboxylate (total yield: 67%). Methyl 5-nitroindole-2-carboxylate was obtained by the nitration of methyl 1-acetylindoline-2-carboxylate acid followed by dehydrogenation with MnO 2 in toluene in 40% total yield.