I. B. Dzvinchuk, M. Lozinskii
Nov 20, 2009
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Journal
Chemistry of Heterocyclic Compounds
Abstract
A three-component cyclocondensation of 4-(dimethylamino)benzaldehyde, 2-phenacyl-1H-benz-imidazoles, and methyl 3-aminobut-2-enoate in refluxing acetic acid occurs via a Hantzsch type reaction and is accompanied by the loss of N,N-dimethylaniline to give the previously unknown methyl 6-aryl-5-(1H-benzimidazol-2-yl)-2-methylnicotinates.