S. El-Basil, K. Ghoneim, M. Khalifa
Jul 1, 1969
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0
Influential Citations
1
Citations
Journal
Journal of pharmaceutical sciences
Abstract
The condensation of 2-chloro-5-nitropyridine with a number of sulfonamides is described. Sulfadiazine, sulfamerazine, sulfathiazole, sulfapyridine, sulfisoxazole, sulfamethoxypyridazine, and sulfadimethoxine afforded the N 4 derivatives via the application of Banks' procedure. 4-Homosulfanilamide using Ullmann's and Mangini's conditions, yielded the N 1 and N 4 derivatives, respectively. With benzylsulfonamide and benzenesulfonamide adopting Ullmann's method the corresponding N -substituted derivatives were obtained.