F. Giraud, P. Marchand, D. Carbonnelle
Sep 1, 2010
Citations
0
Influential Citations
5
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
N-aryl-3-(indol-3-yl)propanamides were synthesized and their immunosuppressive activities were evaluated. This study highlighted the promising potency of 3-[1-(4-chlorobenzyl)-1H-indol-3-yl]-N-(4-nitrophenyl)propanamide 15 which exhibited a significant inhibitory activity on murine splenocytes proliferation assay in vitro and on mice delayed-type hypersensitivity (DTH) assay in vivo.