M. Abualreish, Anwar E. M. Nor E. Ljaleel, Himat M.A. Fadul
Dec 13, 2014
Citations
0
Influential Citations
4
Citations
Journal
International Journal of Algebra and Computation
Abstract
The compound 3-Hydroxy-4'-methoxychalcone (1) was prepared by reacting 3-hydroxybenzaldehyde with 4-methoxyacetophenone. The aminomethylation of this chalcone was accomplished by reaction with formaldehyde and N-methylpiperazine in dry acetonitrile to Obtain 3-hydroxy-4'-methoxy-4-(N-methyl-piperazinomethyl) chalcone (2) and 3-hydroxy-4'-methoxy-2,4-bis-(N-methylpiperazinomethyl)chalcone(3). The products were purified by column and thin layer chromatography and were identified along with their intermediates by spectroscopic methods: UV, IR, NMR and mass spectrometry.