Alexey A Tsygankov, M. Chun, Alexandra D. Samoylova
Dec 15, 2016
Citations
0
Influential Citations
4
Citations
Journal
Synlett
Abstract
Abstract A series of N,N′-dialkylated derivatives of (1R,2R)-cyclohexane-1,2-diamine were synthesized, and a new approach to the one-pot preparation of this type of amine was demonstrated. The prepared diamines were used as organocatalysts for the two-step synthesis of α-hydroxy γ-keto esters from arenes, chlorooxoacetates, and ketones; they were also used as chiral ligands for Meervein–Ponndorf–Verley reductions and Henry reactions.