E. A. Shafikova, D. V. Petrov, T. Sapozhnikova
Sep 26, 2009
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Journal
Chemistry of Heterocyclic Compounds
Abstract
Condensation of exo-2-amino-exo-3-aminomethylnorbornane with acetone, methyl cyclopropyl ketone, cyclohexanone, urea, and formic, acetic, and benzoic acids gave norbornane series tetra- and hexa-hydropyrimidines. It was found that 4-cyclopropyl-4-methyl-exo-3,5-diazatricyclo[6.2.1.02,7]undecane and 4-methyl-exo-3,5-diazatricyclo[6.2.1.02,7]undec-3-ene show analgesic activity.