M. R. Poor Heravi, Sana Hemmati, N. Nami
Jan 13, 2020
Citations
0
Influential Citations
3
Citations
Journal
Polycyclic Aromatic Compounds
Abstract
Abstract A series of novel 5-amino-2-oxo-7-aryl-3,7-dihydro-2H-pyrano[2,3-d]thiazole-6-carbonitriles 5a–j have been synthesized by adopting a facile and simple methodology. The reaction of monochloroacetic acid (1), thiourea (2), aryl and aliphatic aldehydes 3a–j and malononitrile (4) in trifluoroethanol (TFE) under ultrasound irradiation condition afforded 2 H-pyrano[2,3-d]thiazole-6-carbonitriles (5a–j). The remarkable advantages of this method are the simple procedure; high yields, short rection time and environmentally benign method are the advantages of this protocol.