Li Ke-liang
2007
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Journal
Chinese Journal of Synthetic Chemistry
Abstract
A novel branched polyethylene glycol[Glu(PEG)2],which consists of two PEG chains and a glutamic acid(Glu) with a active amido protected by t-butyloxycarbonyl(Boc),was synthesized.Two linear PEG chains in Glu(PEG)2 were linked up through two carboxylic group of the Glu by using 4-dimethylaminopyridine-dicyclohexylcarbodiimide as a catalytic system.The structure of Glu(PEG)2 was confirmed by 1H NMR,IR,GPC and VPO.