E. Lee-Ruff, R. Margau
Feb 28, 2001
Citations
0
Influential Citations
12
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
A series of 2′,3′-dideoxynucleosides based on the apiose family was prepared from photochemical ring-expansion of a common cyclobutanone precursor. The starting ketone, (±) 3-[2′-(benzoyloxy)ethyl]-2,2-dimethylcyclobutanone (12) was prepared from commercially available (±)α-pinene. Since the optically pure antipodes of α-pinene are also commercially available, these nucleosides can be prepared optically pure using the identical procedure.