Monica Mihorianu, I. Mangalagiu, P. Jones
2010
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Journal
ChemInform
Abstract
InnoChemTech GmbH, Hagenring 30, 38106 Braunschweig, Germany Received March 30, 2010 An new, efficient synthesis of imidazo[1,5-a]pyridine derivatives starting from (3-chloro-5-(trifluoromethyl)pyridine-2-yl)methanamine(1) has been developed. A protocol to a 100 g scale synthesis of the amine (1) is given. Good yields are obtained. The structures of two products were confirmed by single crystal X-ray methods