A. A. Napoleon, V. Sharma, Kadirappa Aggile
Nov 1, 2017
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Journal
IOP Conference Series: Materials Science and Engineering
Abstract
In the present work, anti-inflammatory drug based novel isochromen-1-one, their thio and N-methylated analogues were synthesized from the etodolac bulk drug, 1. All the synthesized compounds were purified and successfully characterized by FT-IR, 1H NMR, 13C NMR and Mass spectroscopy. All the derivatives procured are with remarkable yields from 67-72%.