Liangxi Li
2011
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Journal
Chinese Journal of Synthetic Chemistry
Abstract
In order to prepare novel compound of more antidepressant effect,an antidepressant duloxetine was pieced together with substituted acyl chloride by N-acylation and N-alkylation,respectively to synthesiz five novel N-substituted-acyl-N-methyl-3-(naphthalene-1-yloxy)-3-(2-thienyl)propanamines.The structures were characterized by 1H NMR,IR and MS.