B. Raju
2008
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Journal
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry
Abstract
4-Benzyloxy-3,5-dimethylphenylacetate 1 reacts with substituted benzyl amines 2a-e affords N-substituted benzyl-2-(4'-benzyloxy-3',5'-dimethylphenyl) acetamides 3a-e, which on debenzylation give N-substituted benzyl-2-(3',5'-dimethyl-4'-hydroxy phenyl) acetamides 4a-e in very good yields which are important intermediates for the synthesis of 1,2,3,4-tetrahydroisoquinolines.