Chuancheng Zhang, Qiang Yue, Zhen-Hua Xiao
Jul 3, 2017
Citations
1
Influential Citations
5
Citations
Journal
Synthesis
Abstract
Abstract An efficient protocol for the synthesis of O-aroyl-N,N-dimethylhydroxylamines, which are important electrophilic amination reagents, is described. The reaction between carboxylic acids and N,N-dimethylformamide is mediated by hypervalent iodine and occurs under mild conditions at room temperature to give the desired products in good yields. The process shows good functional group compatibility and air and moisture tolerance.