H. Kimura, Keiichi Tsuto
Oct 1, 1993
Citations
0
Influential Citations
21
Citations
Journal
Journal of the American Oil Chemists’ Society
Abstract
Abstractdl-serine (dl-Ser), glycine (Gly), serinol (SerOH) and related compounds were catalytically derived from glycerol (GLY). Catalytic oxidation in the presence of ammonia of GLY, followed by hydrogen treatment over noble metals, to achieve direct synthesis of amino acids is not practical. Reductive amination over an Ru-Pd/C catalyst of glyceric acid, one of the oxidation products of GLY, was effective fordl-Ser synthesis. Gly was catalytically formed fromdl-Ser by dehydrogenation and decarbonylation in hydrogen atmosphere. Catalytic oxidation of SerOH prepared by reductive amination over an Rh-Pd/C catalyst of dihydroxyacetone, another oxidation product of GLY, was also effective fordl-Ser synthesis. A new route fordl-Ser and Gly from GLY is presented.dl-alanine and γ-aminobutyric acid also formed, depending on reaction conditions.