Qiu Fang-li
2012
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Journal
Applied Chemical Industry
Abstract
(E)-4-morpholine-2-butenoic acid hydrochloride was synthesized from morpholine and 4-bromo-2-butenoic acid methyl ester obtained from 4-morpholine methyl crotonate.Then it was hydrolysised by hydrochloric acid in dioxane.The overall yield of target product was 49.65%.The product was characterized by 1H NMR spectrometry.