Wang Junming
2013
Citations
0
Influential Citations
2
Citations
Journal
Chinese Journal of Pharmaceuticals
Abstract
(S)-1-Boc-3-hydroxypiperidine was synthesized from 3-hydroxypyridine by hydrogenation catalyzed by 5%Rh/C,chiral resolution with(2S,3S)-N-(4-chlorophenyl)-2,3-dihydroxy-succinamic acid,the derivative of D-tartaric acid,and then reaction with(Boc)2O in the presence of triethylamine.The overall yield was about 40%.