Junzo Nolcami, T. Mandai*, A. Nishimura
1986
Citations
0
Influential Citations
28
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Reaction of optically active 2-(p-chlorophenylsulfinyl)acetonitrile ((R)- 1a ) with aldehydes, in the presence of piperidine in acetonitrile at r.t., gave optically active 4-hydroxyalk-2-enenitriles in good optical and chemical yields. The absolute configuration of (−)-4-hydroxypent-2-enenitrile, predominantly obtained by the reaction of (R)- 1a with propanal, was determined to be R.