K. Koh, R. Ben, T. Durst
Jan 17, 1994
Citations
0
Influential Citations
20
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 2,5-Dibromoadipic acid has been converted into the di-(R)-pantolactone ester of (S,S)-pyyrolidine-2,5-dicarboxylic acid in two steps. This compound serves as a precursor to C 2 -symmetric 2,5-disubstituted pyrrolidines. The synthesis of linear C 2 -symmetric β,β′-dihydroxyamines starting with α-bromophenylacetic acid and (S)-phenylglycine ethyl ester is also reported.