N. Kato, H. Okamoto, H. Takeshita
Mar 11, 1996
Citations
0
Influential Citations
33
Citations
Journal
Tetrahedron
Abstract
Starting from condensation of two iridoid synthons, (3S,8R)-benzyloxy-1-iriden-7-al and (3R)-7-chloro-1-iridene, cotylenol, one of the representative fusicoccane diterpenoids having 5-8-5-membered tricyclic carbon framework, is now synthesized for the first time via an eight-membered ring formation by an intramolecular ene reaction and subsequent introduction of an α-hydroxyl group.