M. Bogenstatter, W. Steglich
May 26, 1997
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron
Abstract
Abstract Optically pure α-hydroxyglycine peptides can be prepared by enzymatic resolution of DL-α-(benzyloxy)glycine peptide esters with subtilisin Carlsberg followed by hydrogenolysis of the benzyl protecting group. The DL-α-(benzyloxy)glycine peptide esters were obtained from the corresponding serine derivatives via lead tetraacetate oxidation and reaction of the resulting electrophilic glycine equivalents with benzyl alcohol.