Yan-Wu Li, Yan Liu, Yuntao Jia
Mar 1, 2013
Citations
0
Influential Citations
4
Citations
Journal
Chinese Chemical Letters
Abstract
Abstract A facile synthetic route of linezolid 1 has been developed. Using commercially available ( R )-epichlorohydrin as the starting material, 1 was obtained through a sequence of cyclization, substitution, a Goldberg coupling, aminolysis and acetylation reactions. The synthetic route is easy to perform and can be scaled up.