Y. Kojima, N. Kato
Apr 1, 1980
Citations
0
Influential Citations
4
Citations
Journal
Agricultural and biological chemistry
Abstract
A new synthetic route to perhydrofuro [2, 3-b] furan was developed by employing 3-substituted furan derivatives (t-butyl and phenyl systems) that were derived by coupling reaction with epoxides and a new reagent, lithium di (3-furyl) cuprate. The synthesized furo-furan compounds were prepared to various derivatives for testing antifeeding activities. The results suggest that higher degree activities depend on the presence of a moderately polar, substituent group. Moreover, in order to enhance the antifeeding activities, the hydroxy group of the hem iacetal should be protected with an acyl or methyl group.