A. Agababyan, G. Gevorgyan, D. Sarkisyan
Jun 1, 2002
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Journal
Pharmaceutical Chemistry Journal
Abstract
The aminomethylation reactions were conducted either in acetic acid or in a mixture of acetic acid with dioxane (2 : 1). Dihydrochlorides I and II, belonging to 1,6-hexanediones (n = 2), are stable crystalline substances, whereas many of the 1,8-hexanedione dihydrochlorides III and IV (n = 4) are hygroscopic. The proposed structures of the synthesized compounds were confirmed by IR and H NMR spectroscopic data.