Indira Sen, Swarnendu Sasmal, S. Ghorai
Jul 29, 2015
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Influential Citations
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Journal
Tetrahedron Letters
Abstract
A convenient and high yielding total synthesis of phebalosin (1) has been achieved in four linear steps from commercially available umbelliferone. The first total synthesis of murraxocin (4), a natural product isolated from Murraya exotica has been described via phebalosin. Total syntheses of murrangatin (2) and murralongin (5) have also been demonstrated using the same strategy. The key step involves a Corey–Chaykovsky reaction to construct the isopreneepoxide unit.