H. Chiu, D. Tzou, L. Patkar
Jun 12, 2003
Citations
0
Influential Citations
24
Citations
Journal
The Journal of organic chemistry
Abstract
In the present study, an efficient method with a high overall yield for preparing phytosphingosine and an analogue was developed. Starting with commercially available 2,3;5,6-di-O-isopropylidene-d-mannofuranose, a variety of lipid moieties were incorporated to obtain phytosphingosine and an analogue. Through an eight-step manipulation, phytosphingosine was obtained with an overall yield of 57%.