V. Dotsenko, I. Ukrainets, D. Tebiev
Nov 1, 2016
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Abstract
The reaction of S-alkyl thiobarbiturates with aromatic aldehydes and malononitrile (or arylmethylidenemalononitrile) leads to hitherto unknown 4Н-pyrano[2,3-d]pyrimidines. Plant growth regulating activity and herbicide antidote activity were studied in the series of the obtained compounds. We found that ethyl {[7-amino-6-cyano-5-(4-methoxyphenyl)-4-oxo-3,5-dihydro-4Н-pyrano[2,3-d]pyrimidin-2-yl)thio}acetic acid revealed moderate activity as 2,4-D antidote.