Judith H. Cohen, M. Bos, Sergio Cesco‐Cancian
Oct 1, 2003
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0
Influential Citations
14
Citations
Journal
Organic Process Research & Development
Abstract
Elarofiban is a novel, nonpeptide, orally active fibrinogen receptor antagonist useful for the treatment of platelet mediated thrombotic disorders (Costanzo, M. J.; Hoekstra, W. J.; Maryanoff, B. E. WO, 97/41102, 1997). Herein we describe the process research that was carried out for the synthesis of elarofiban that eventually led to the development of a safe and cost-effective commercial scale process.