A. Alizadeh, Tahereh Firuzyar, Azadeh Mikaeili
May 1, 2013
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0
Influential Citations
17
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
An efficient, one-pot synthetic protocol for polyfunctionalized 1,4-dihydropyridine-fused-1,3-diazaheterocycles, a class of biologically active compounds, starting from 1,1-bis(methylthio)-2-nitroethylene, 1,n-diamine, arylaldehyde, and malononitrile is described. The reactions are completed within 12–15 h under refluxing conditions and in the presence of 10 mol % of piperidine as a basic catalyst to produce the title compounds in 60–75% yields.