C. Fink, A. Spada, D. Colussi
Jun 1, 1992
Citations
0
Influential Citations
4
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract This report describes the preparation of (R)-(3-chloro-2-thienyl)-2-butylamine and its conversion to the titled N6-substituted adenosine agonist, RG 14718(−). RG 14718(−) was found to have exceptional affinity and selectivity for the adenosine A1 receptor, IC50 = 5.7 + /− 1.6 pM.