Qianqian Li, Zhongmei Wu, Min Zhang
2020
Citations
0
Influential Citations
1
Citations
Journal
Chinese Journal of Organic Chemistry
Abstract
The synthesis of isoxazole derivatives has been paid much attention by organic synthetic chemists because isoxazoles usually exhibit good biological activity such as insecticidal and bactericidal activity. In this study, a series of 3-aryl-4-arylamine methyl isoxazole derivatives were synthesized from ethyl 3-arylisoxazole-4-carboxylate by reduction, bromination and substitution reaction. The synthesized compounds were identified by 1 H NMR, 13 C NMR and HRMS, and the preliminary bioactivity test results showed that some compounds obtained had good inhibitory effects anainst aphids and armyworms.