D. Pitushkin, V. Burmistrov, G. Butov
Aug 1, 2020
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Journal
Russian Journal of Organic Chemistry
Abstract
The reaction of bicyclo[2.2.1]hept-5-en-2-yl isocyanate with fluoro- and chloro-substituted anilines was used to synthesize in a yield of 25–68% a series of 1,3-disubstituted ureas containing a lipophilic group in their structure. The synthesized ureas are promising as inhibitors of RNA virus replication and human soluble epoxide hydrolase.