R. A. Kuroyan, V. V. Sarkisyan, S. Vartanyan
Dec 1, 1986
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Journal
Chemistry of Heterocyclic Compounds
Abstract
Bromination of 1-methylpiperidine-4-carboxaldehyde gave 4-bromo-1-methylpiperidine-4-carboxaldehyde hydrobromide which was used to synthesize 1,4,9-triazaspiro[5,5]undecane and 3,7,11-triazaspiro[5,6]dodecane. Cyanoethylation and alkylation with various alkyl halides gave their mono- and di-substituted derivatives. The side chain nitrile group was reduced and the hydrazide was obtained from the ester analog.