K. Shinozuka, M. Onodera, H. Ikeda
Nov 1, 1999
Citations
0
Influential Citations
0
Citations
Journal
Nucleic acids symposium series
Abstract
Oligodeoxynucleotides containing a 2-fluoro-2'-deoxyinosine residue substituting normal 2'-deoxyguanosine residue were synthesized. Upon treating with ethanol solution of polyamine, the fluorine atom in the oligomers were readily substituted with the polyamine. The thermal stabilities of the duplexes consisted of the polyamine-bearing oligomers and their cDNAs as well as their RNA cleaving activity were investigated.