Xu Xiu-zh
2014
Citations
0
Influential Citations
0
Citations
Journal
Strait Pharmaceutical Journal
Abstract
OBJECTIVE To study on the synthesis of a water soluble cationic octasubstituted phthalocyaninatozinc and its spectral properties. METHODS The precursor 4,5-bis( pyridin-3-yloxy) phthalonitrile was synthesized from the nucleophilic substitution reaction of 4-bromo-5-nitrophthalonitrile and pyridin-3-ol. The corresponding octasubstituted phthalocyaninatozinc,ZnPcBPO8,was prepared by the condensation reaction of 4,5-bis( pyridin-3-yloxy) phthalonitrile and anhydrous Zn( OAc)2. The prepared ZnPcBPO8was converted to water soluble ZnPcBPO8I8by quaternizing with methyl iodide. UV-vis and fluorescence spectra of ZnPcBPO8I8were determined. RESULTS The maximum absorbance of ZnPcBPO8I8was 673nm in DMF and its emission wavelength was gradually red shift with the concentration. ZnPcBPO8I8was aggregation in water and its monomer increases with the percent of ethanol,which maximum content of monomer was obtained in 70% ethanol. However,ZnPcBPO8I8exits mainly as monomer at pH 5 or 9 and assembles with the increases of acidity or alkalinity. CONCLUSION These results indicates that ZnPcBPO8I8has good water solubility and its monomer-aggregate may convert to each other at different condition.