G. Just, C. Simonovitch, F. Lincoln
Sep 10, 1969
Citations
0
Influential Citations
35
Citations
Journal
Journal of the American Chemical Society
Abstract
Details are provided of a synthesis of PGF1alpha (prostaglandin F1alpha) PGF1beta and several other PGs isomeric with these. Epoxybicyclo[3.1.0]hexane derivatives were used in this synthesis involving an acid-catalyzed opening and rearrangement of the epoxybicyclo[3.1.0] hexanes. The chemical structures of the substances used in and obtained through the process are provided.