A. El-Agrody, M. H. El-Hakim, M. El-latif
2000
Citations
0
Influential Citations
101
Citations
Quality indicators
Journal
Acta Pharmaceutica
Abstract
Several new naphtho[1',2':5,6]pyrano[2,3-d]pyrimidines (4, 5, 7, 8) were obtained by the reaction of enaminonitrile (3) and 2-ethoxymethylideneamino naphtho[2,1-b]-pyrane (6) with suitable reagents such as carboxylic acid derivatives, CS 2 , C 6 H 5 NSC, ammonia, hydrazine, amines and H 2 S, respectively. Polysubstituted pyrano[3,2-e]-[1,2,4]triazolo[2,3-c]pyrimidines (9, 13) were also prepared. Antimicrobial activities of the synthesised compounds were studied. Some of the compounds gave promising results.