Yunhui Zhao, Yubo Li, T. Guo
May 25, 2016
Citations
0
Influential Citations
34
Citations
Journal
Tetrahedron Letters
Abstract
A novel and efficient route for the generation of pyrazolo[5,1-a]isoquinolines via 1,3-dipolar cycloaddition reaction of 1,3-dipolar and ethyl acetoacetate is described. Meanwhile, the selective synthesis of either pyrazolo[5,1-a]isoquinoline-1-carboxylate or 2-(pyrazolo[5,1-a]isoquinolin-2-yl)acetate derivatives from the same reactants has been achieved by simply varying base and reaction conditions.