G. Anderson
Sep 1, 1985
Citations
0
Influential Citations
19
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The reaction of diethyl ethoxymethylenemalonate (1) and 6-amino-1,3-dimethyluracil (2) was determined to be regioselective. Under acidic conditions the product was the previously isolated 7-oxopyrido[2,3-d]pyrimidine (3), while in the presence of one equivalent of base followed by thermal cyclization, the isomeric 5-oxopyrido[2,3-d]pyrimidine (5) is formed.