T. Lash, J. Bellettini, J. Bastian
1994
Citations
0
Influential Citations
44
Citations
Journal
Synthesis
Abstract
Benzyl esters of 5-unsubstituted pyrrole-2-carboxylic acids were prepared in excellent yields by the base-catalyzed condensation of benzyl isocyanoacetate with α-acetoxynitro compounds, or nitroalkenes, in refluxing tetrahydrofuran. These pyrrolic products are important intermediates in the synthesis of porphyrins and related compounds