I. Sánchez, M. Pujol
Apr 23, 1999
Citations
0
Influential Citations
19
Citations
Journal
Tetrahedron
Abstract
Abstract The pyrrolo[2,1- c ][1,4]benzoxazine system was synthesized from 2-fluoroaniline involving an intramolecular nucleophilic displacement of the fluoride atom. The intermediate alcohols 7a and 10 were treated in basic media under strictly controlled conditions which led to the desired tricyclic structure. The unsubstituted alcohol 10 was more stable than the substituted one.