Chin-shu Cheng, G. Hoops, R. A. Earl
Apr 1, 1997
Citations
0
Influential Citations
8
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract The N-3- and N-2-methylated analogs of several 5-substituted 2 amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-4-ones were synthesized from 5-cyano-2,4-dichloro-7-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine (10). These compounds are analogs of nucleoside Q that are methylated in a manner similar to some of the naturally occurring methylated guanosines. Present Address: 663 Moorpark Way, Mountain View, CA 94041 Present Address: Pharmacy Building, Purdue University, West Lafayette, IN 47907-1333 Present Address: Department of Chemist, North Island College 2300 Ryan Road, Courtenay, BC V9N 8N6, Canada