D. Sharma, B. Narasimhan, Pradeep Kumar
Mar 1, 2009
Citations
0
Influential Citations
73
Citations
Quality indicators
Journal
European journal of medicinal chemistry
Abstract
A series of 2-(substituted phenyl)-1H-benzimidazole (1-10) and [2-(substituted phenyl)-benzimidazol-1-yl]-pyridin-3-yl-methanone (11-19) derivatives were synthesized and tested in vitro for their antimicrobial activity. The results of QSAR investigation indicated the importance of molecular descriptors, dipole moment (mu), log of octanol water partition coefficient (logP) and second order molecular connectivity index ((2)chi) in describing the antimicrobial activity of the synthesized compounds.