B. Desai, Dinesh Sureja, Y. Naliapara
Aug 1, 2001
Citations
5
Influential Citations
112
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry
Abstract
Synthesis and QSAR studies of the title compounds have resulted in the identification of structural and physicochemical parameters (MR, sigma(o), sigma(m), sigma(p)) contributing to antitubercular activity. Among these, carbamoyl phenyl ring substituted at 3 and 4 position with NO(2) group or 2 position with Cl or OCH(3) group shows >90% inhibition against H(37)Rnu comparable to other substituted phenyls.