H. Hamada, T. Miura, H. Kumobayashi
Oct 1, 2001
Citations
0
Influential Citations
27
Citations
Journal
Biotechnology Letters
Abstract
The asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol, a precursor for a key intermediate of an important class of drugs, was achieved by reduction of the corresponding ketone using an acetone powder of Geotrichum candidum with 98% ee and 94% yield based on the starting amount of ketone.