Guangfei Huang, R. Hollingsworth
Dec 11, 1998
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Journal
Tetrahedron-asymmetry
Abstract
Abstract A short, efficient synthesis of (R)-3-hydroxytetradecanoic acid, a key component of bacterial endotoxins, using (R)-oxirane acetic acid ethyl ester as the source of chirality is described. The method is general and can be used in the preparation of other chiral 3-hydroxy acids.