Y. Azuma, M. Morone, K. Nagayama
Jun 1, 2003
Citations
0
Influential Citations
5
Citations
Journal
Heterocycles
Abstract
I he chlorination of 1,2-dihydro-4-hydroxy-6-methyl-2-oxo-3-pyridinecarbonitrile (2) with a mixture of POCl 3 and PCl 5 in CHCl 3 gave 4-chloro-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile (3) in good yield. Compound (3) reacted with alkyl- and arylamines to give the corresponding 4-alkylamino- and 4-arylamino-3-pyridinecarbonitriles (6 and 7).